Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.72 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.72 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.67 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8435757 | 0.99 | CHRNB2 (0.71) | CHRNB2CHRNA4CHRNA3CHRNB4 | |
| Hydrochloric Acid SCHEMBL7464295 | 0.99 | CHRNB2 (0.71) | CHRNB2CHRNA4CHRNA3CHRNB4 | |
| SCHEMBL7408268 | 0.90 | CHRNB2 (0.60) | CHRNB2CHRNA4CHRNA3CHRNB4 | |
| SCHEMBL28209799 | 0.90 | CHRNB2 (0.60) | CHRNB2CHRNA4CHRNA3CHRNB4 | |
| SCHEMBL905204 | 0.90 | CHRNB2 (0.60) | CHRNB2CHRNA4CHRNA3CHRNB4 | |
| Hydrochloric Acid SCHEMBL7408492 | 0.88 | CHRNB2 (0.63) | CHRNB2CHRNA4CHRNA3CHRNB4 | |
| Pozanicline SCHEMBL194037 | 0.84 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA3CHRNB4 | |
| Pozanicline SCHEMBL29378392 | 0.84 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA3CHRNB4 | |
| Pozanicline SCHEMBL1538473 | 0.84 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA3CHRNB4 | |
| Pozanicline SCHEMBL7367252 | 0.84 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA3CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948793-A | 3-pyridyloxymethyl heterocyclic ether compounds useful in controlling neurotransmitter release | ABBOTT LABORATORIES (US) | 1999-09-07 | — | — | US | disclosed |
| US-5914328-A | CONTROL DOPAMINE RELEASE, ACTIVATE CHOLINERGIC CHANNELS | ABBOTT LABORATORIES (US) | 1999-06-22 | — | — | US | disclosed |