Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11763231 | 0.83 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10NPSR1GLO1 | |
| SCHEMBL9823358 | 0.83 | ALDH1A1 (0.62) | ALDH1A1LMNAHSD17B10NPSR1GLO1 | |
| SCHEMBL7262 | 0.83 | ALDH1A1 (0.62) | ALDH1A1LMNAHSD17B10NPSR1GLO1 | |
| SCHEMBL1331989 | 0.83 | ALDH1A1 (0.62) | ALDH1A1LMNAHSD17B10NPSR1GLO1 | |
| SCHEMBL28365143 | 0.81 | ALDH1A1 (0.46) | ALDH1A1LMNAHSD17B10NPSR1GLO1 | |
| Ammonia Solution, Strong SCHEMBL12803984 | 0.80 | ALDH1A1 (0.59) | ALDH1A1LMNAHSD17B10NPSR1GLO1 | |
| SCHEMBL28824460 | 0.80 | ALDH1A1 (0.59) | ALDH1A1LMNAHSD17B10NPSR1GLO1 | |
| SCHEMBL9751764 | 0.80 | ALDH1A1 (0.59) | ALDH1A1LMNAHSD17B10NPSR1GLO1 | |
| SCHEMBL28251428 | 0.80 | ALDH1A1 (0.59) | ALDH1A1LMNAHSD17B10NPSR1GLO1 | |
| SCHEMBL30076441 | 0.80 | ALDH1A1 (0.59) | ALDH1A1LMNAHSD17B10NPSR1GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728315-B1 | PHOTOCHROMIC COMPOSITIONS OF IMPROVED FATIGUE RESISTANCE | PPG IND OHIO INC (US) | 1999-12-22 | — | — | EP | disclosed |
| EP-0728315-A1 | PHOTOCHROMIC COMPOSITIONS OF IMPROVED FATIGUE RESISTANCE | PPG INDUSTRIES, INC. (US) | 1996-08-28 | — | — | EP | disclosed |
| EP-0728315-A4 | PHOTOCHROMIC COMPOSITIONS OF IMPROVED FATIGUE RESISTANCE | PPG INDUSTRIES INC (US) | 1995-11-23 | — | — | EP | disclosed |
| US-5391327-A | Includes hindered amine ligth stabilizer and asymmetric diaryloxalamide light stabilizer | TRANSITIONS OPTICAL, INC. (US) | 1995-02-21 | — | — | US | disclosed |
| WO-1994008260-A1 | PHOTOCHROMIC COMPOSITIONS OF IMPROVED FATIGUE RESISTANCE | PPG INDUSTRIES, INC. (US) | 1994-04-14 | — | — | WO | disclosed |