Malonic Acid

Malonic Acid

SCHEMBL8436854

CCCCCCCCCCCC[N+](C)(C)C.CCCCCCCCCCCC[N+](C)(C)C.O=C([O-])CC(=O)[O-]

nearest known ligand 0.62

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 7/20 0.62
APAF1 O14727 1/20 0.58
HSP90AA1 P07900 1/20 0.58
RAD52 P43351 1/20 0.58
LSS P48449 1/20 0.46
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
APEX1 P27695 3/20 0.46
NFKB1 P19838 2/20 0.46
KDM4E B2RXH2 2/20 0.46
ACHE P22303 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
PMP22 Q01453 2/20 0.46
LMNA P02545 1/20 0.46
HSD17B10 Q99714 1/20 0.46
HRH3 Q9Y5N1 1/20 0.46
TSHR P16473 1/20 0.46
RAB9A P51151 1/20 0.46
CPT2 P23786 2/20 0.45
CPT1A P50416 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Malonic Acid SCHEMBL8437815 1.00 DNM1 (0.62) DNM1APAF1HSP90AA1RAD52LSS
Cetrimonium SCHEMBL8434403 1.00 DNM1 (0.62) DNM1APAF1HSP90AA1RAD52LSS
Cetrimonium SCHEMBL8434407 0.90 DNM1 (0.56) DNM1APAF1HSP90AA1RAD52LSS
Malonic Acid SCHEMBL8437823 0.90 DNM1 (0.56) DNM1APAF1HSP90AA1RAD52LSS
Malonic Acid SCHEMBL8436857 0.90 DNM1 (0.56) DNM1APAF1HSP90AA1RAD52LSS
Propionic Acid SCHEMBL5575004 0.89 DNM1 (0.65) DNM1APAF1HSP90AA1RAD52LSS
Propionic Acid SCHEMBL5574446 0.89 DNM1 (0.65) DNM1APAF1HSP90AA1RAD52LSS
Cetrimonium SCHEMBL31516838 0.89 DNM1 (0.65) DNM1APAF1HSP90AA1RAD52LSS
Propionic Acid SCHEMBL5571634 0.89 DNM1 (0.65) DNM1APAF1HSP90AA1RAD52LSS
Propionic Acid SCHEMBL5571712 0.89 DNM1 (0.65) DNM1APAF1HSP90AA1RAD52LSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5933693-A Electroconductive elastic member and electrophotographic apparatus using same BRIDGESTONE CORPORATION (JP) 1999-08-03 US disclosed