Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8432474 | 0.98 | MEN1 (0.51) | CHRM2MEN1KMT2ATSHRKDM4E | |
| SCHEMBL13330470 | 0.90 | MEN1 (0.49) | CHRM2MEN1KMT2ATSHRKDM4E | |
| SCHEMBL12963417 | 0.84 | MEN1 (0.51) | CHRM2MEN1KMT2ATSHRKDM4E | |
| SCHEMBL6293512 | 0.83 | MEN1 (0.50) | CHRM2MEN1KMT2ATSHRKDM4E | |
| Formic Acid SCHEMBL6324510 | 0.82 | MEN1 (0.50) | CHRM2MEN1KMT2ATSHRKDM4E | |
| SCHEMBL10032820 | 0.82 | BCHE (0.64) | CHRM2MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL8882896 | 0.79 | MEN1 (0.69) | MEN1KMT2ATSHRKDM4ESMN1; SMN2 | |
| SCHEMBL4916089 | 0.79 | CHRM2 (0.81) | CHRM2MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL19325340 | 0.79 | MEN1 (0.47) | MEN1KMT2ATSHRKDM4ESMN1; SMN2 | |
| SCHEMBL3544426 | 0.79 | KMT2A (0.51) | MEN1KMT2AKDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714155-A | ANTIINFLAMMATORY AGENTS; TOPICAL; SUBSTANCE P ANTAGONIST | SOCIETE L'OREAL S.A. (FR) | 1998-02-03 | — | — | US | claimed |
| US-5968532-A | SUBSTANCE P ANTAGONISTS | SOCIETE L'OREAL S.A. (FR) | 1999-10-19 | — | — | US | disclosed |
| US-5714155-A | ANTIINFLAMMATORY AGENTS; TOPICAL; SUBSTANCE P ANTAGONIST | SOCIETE L'OREAL S.A. (FR) | 1998-02-03 | — | — | US | disclosed |