Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.86 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.86 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.86 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 4/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | LDHA | P00338 | 2/20 | 0.46 |
| ▸ | LDHB | P07195 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | THPO | P40225 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urea SCHEMBL8433985 | 1.00 | — | — | |
| Urea SCHEMBL8434163 | 1.00 | LMNA (0.86) | LMNAALDH1A1TDP1OR51E2ACHE | |
| Urea SCHEMBL8435946 | 1.00 | LMNA (0.86) | LMNAALDH1A1TDP1OR51E2ACHE | |
| Urea SCHEMBL8561785 | 1.00 | LMNA (0.86) | LMNAALDH1A1TDP1OR51E2ACHE | |
| Urea SCHEMBL28967154 | 0.94 | — | — | |
| Urea SCHEMBL8560069 | 0.93 | LMNA (1.00) | LMNAALDH1A1TDP1OR51E2ACHE | |
| Urea SCHEMBL7756359 | 0.93 | LMNA (1.00) | LMNAALDH1A1TDP1OR51E2ACHE | |
| Urea SCHEMBL20641124 | 0.93 | LMNA (1.00) | LMNAALDH1A1TDP1OR51E2ACHE | |
| Urea SCHEMBL411583 | 0.93 | — | — | |
| Urea SCHEMBL8434002 | 0.93 | LMNA (1.00) | LMNAALDH1A1TDP1OR51E2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922654-A | TWO OR MORE ORGANOMETALLIC COMPOUNDS WHERE THE METAL IS A TRANSITION METAL OR SEMIMETAL, OR ZINC; FOR EXAMPLE, ZINC DIALKYLDITHIOPHOSPHATE, OR NICKEL DIALKYLDITHIOCARBAMATE; HIGHER LOAD BEARING PROPERTIES, HIGH TEMPERATURE PERFORMANCE | NSK LTD. (JP) | 1999-07-13 | — | — | US | disclosed |