Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 17/20 | 0.84 |
| ▸ | RARB | P10826 | 16/20 | 0.84 |
| ▸ | RARA | P10276 | 15/20 | 0.84 |
| ▸ | RXRA | P19793 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765899 | 0.91 | RARG (1.00) | RARGRARBRARARXRALMNA | |
| SCHEMBL8766285 | 0.91 | RARG (1.00) | RARGRARBRARARXRALMNA | |
| SCHEMBL8766454 | 0.91 | RARG (1.00) | RARGRARBRARARXRALMNA | |
| SCHEMBL566680 | 0.86 | RARG (0.66) | RARGRARBRARALMNABLM | |
| SCHEMBL8433269 | 0.85 | RARA (0.67) | RARGRARBRARARXRALMNA | |
| SCHEMBL8433268 | 0.85 | RARA (0.67) | RARGRARBRARARXRALMNA | |
| SCHEMBL8431874 | 0.84 | RARA (0.66) | RARGRARBRARARXRALMNA | |
| SCHEMBL8434108 | 0.84 | RARA (0.66) | RARGRARBRARARXRALMNA | |
| SCHEMBL8431871 | 0.84 | RARG (0.63) | RARGRARBRARARXRALMNA | |
| SCHEMBL8431877 | 0.84 | RARG (0.63) | RARGRARBRARARXRALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776881-B1 | Bi-aromatic compounds comprising an adamantyl group in para-position, pharmaceutical and cosmetic compositions containing them and their utilization | CIRD GALDERMA (FR) | 1999-12-08 | — | — | EP | claimed |