SCHEMBL8437244

SCHEMBL8437244

CCCCOc1cccc(OC(=O)O)c1OCCCC

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 3/20 0.46
LMNA P02545 3/20 0.46
PTGES O14684 2/20 0.46
ALOX5 P09917 2/20 0.46
HIF1A Q16665 2/20 0.46
TSHR P16473 2/20 0.46
CHRM1 P11229 1/20 0.46
ALOX15 P16050 1/20 0.46
ACHE P22303 1/20 0.46
KCNH2 Q12809 1/20 0.46
PPARG P37231 1/20 0.46
CYP1A2 P05177 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.44
KMT2A Q03164 3/20 0.44
MAPT P10636 2/20 0.44
MEN1 O00255 2/20 0.44
NR1I2 O75469 1/20 0.44
CYP3A4 P08684 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8437243 0.89 ELANE (0.50) CHRM2LMNAPTGESALOX5HIF1A
SCHEMBL8091127 0.86 SMN1; SMN2 (0.57) LMNATSHRCYP1A2SMN1; SMN2KMT2A
SCHEMBL6575498 0.85 CYP1A2 (0.53) CHRM2LMNAHIF1ATSHRPPARG
SCHEMBL1238407 0.84 LMNA (0.60) CHRM2LMNAHIF1ATSHRCHRM1
SCHEMBL9774307 0.81 KMT2A (0.51) CHRM2LMNATSHRKMT2AMAPT
SCHEMBL898712 0.80 LMNA (0.58) CHRM2LMNATSHRCYP1A2CYP2C9
SCHEMBL15548129 0.79 CYP1A2 (0.44) CHRM2LMNAPTGESALOX5HIF1A
SCHEMBL5587132 0.79 MEN1 (0.50) CHRM2LMNATSHRKMT2AMAPT
SCHEMBL5587075 0.78 MEN1 (0.52) CHRM2LMNATSHRPPARGKMT2A
SCHEMBL5589212 0.78 MEN1 (0.52) CHRM2LMNATSHRPPARGKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5527875-A Process for producing aromatic polycarbonate MITSUBISHI CHEMICAL CORPORATION (JP) 1996-06-18 US claimed
EP-0703262-B1 Process for producing aromatic polycarbonate MITSUBISHI CHEM CORP (JP) 1999-12-15 EP disclosed
EP-0673959-B1 Process for producing aromatic polycarbonate MITSUBISHI CHEM CORP (JP) 1998-10-28 EP disclosed
EP-0360578-B1 Process for the production of polycarbonates GE PLASTICS JAPAN LTD (JP) 1998-08-05 EP disclosed
US-5578694-A MELT POLYCONDENSATION OF AROMATIC DIOL AND DIARYL CARBONATE; ESTER INTERCHANGE USING PHOSPHONIUM CATALYST MITSUBISHI CHEMICAL CORPORATION (JP) 1996-11-26 US disclosed
US-5527875-A Process for producing aromatic polycarbonate MITSUBISHI CHEMICAL CORPORATION (JP) 1996-06-18 US disclosed
EP-0703262-A2 Process for producing aromatic polycarbonate Mitsubishi Chemical Corporation (JP) 1996-03-27 EP disclosed
EP-0673959-A1 Process for producing aromatic polycarbonate Mitsubishi Chemical Corporation (JP) 1995-09-27 EP disclosed
US-5276129-A Aromatic polycarbonates with excellent color tone, heat resistance and water resistance GE PLASTICS JAPAN, LTD. (JP) 1994-01-04 US disclosed
US-5151491-A Nitrogen compound, a boric acid compound and a dihydroxy compound terminated with a monoalcohol GE PLASTICS JAPAN, LTD. (JP) 1992-09-29 US disclosed
EP-0360578-A2 Process for the production of polycarbonates GE PLASTICS JAPAN LTD. (JP) 1990-03-28 EP disclosed