SCHEMBL8437291

SCHEMBL8437291

C=CCCCCC(C)[SiH](Cl)Cl

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
ALDH1A1 P00352 3/20 0.37
MAPT P10636 2/20 0.33
USP2 O75604 2/20 0.33
CYP3A4 P08684 1/20 0.33
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
LMNA P02545 1/20 0.31
ABCC4 O15439 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28492067 0.98 TSHR (0.43) TSHRALDH1A1MAPTUSP2CYP3A4
SCHEMBL28350398 0.98 TSHR (0.43) TSHRALDH1A1MAPTUSP2CYP3A4
SCHEMBL6037393 0.98 TSHR (0.43) TSHRALDH1A1MAPTUSP2CYP3A4
SCHEMBL28491282 0.98 TSHR (0.43) TSHRALDH1A1MAPTUSP2CYP3A4
SCHEMBL5697571 0.93 TSHR (0.39) TSHRALDH1A1
SCHEMBL5523530 0.85 TSHR (0.38) TSHRALDH1A1MAPTUSP2CYP3A4
SCHEMBL28347430 0.84
SCHEMBL8440544 0.78 TSHR (0.39) TSHRALDH1A1MAPTUSP2CYP3A4
SCHEMBL6037376 0.75 TSHR (0.41) TSHRALDH1A1MAPTUSP2CYP3A4
SCHEMBL11063317 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118063658-A Polybutene-1 and process for preparing same 中国科学院化学研究所 2024-05-24 CN claimed
CN-116199813-A Long chain branched polypropylene and preparation method thereof 中国科学院化学研究所 2023-06-02 CN claimed
CN-112143114-B Long-chain branched polypropylene impact copolymer and preparation method thereof 中国科学院化学研究所 2021-10-22 CN claimed
CN-112143113-B Long-chain branched polypropylene impact copolymer and preparation method thereof 中国科学院化学研究所 2021-09-21 CN claimed
CN-112142897-B Application of organosilane in preparation of linear low density polyethylene, linear low density polyethylene and preparation method and application thereof 中国科学院化学研究所 2021-07-27 CN claimed
CN-112142894-B Application of organosilane in preparation of high-density polyethylene, high-density polyethylene and preparation method and application thereof 中国科学院化学研究所 2021-05-25 CN claimed
CN-112142894-A Application of organosilane in preparation of high-density polyethylene, high-density polyethylene and preparation method and application thereof 中国科学院化学研究所 2020-12-29 CN claimed
CN-112142895-A Application of organosilane, random copolymerization polypropylene and preparation method thereof 中国科学院化学研究所 2020-12-29 CN claimed
CN-112143114-A Long-chain branched polypropylene impact copolymer and preparation method thereof 中国科学院化学研究所 2020-12-29 CN claimed
CN-112142897-A Application of organosilane in preparation of linear low density polyethylene, linear low density polyethylene and preparation method and application thereof 中国科学院化学研究所 2020-12-29 CN claimed
CN-112143113-A Long-chain branched polypropylene impact copolymer and preparation method thereof 中国科学院化学研究所 2020-12-29 CN claimed
CN-108659151-B Application of organosilane, polypropylene and preparation method of polypropylene 中国科学院化学研究所 2020-01-10 CN claimed
CN-116199813-B Long chain branched polypropylene and preparation method thereof 中国科学院化学研究所 2025-02-11 CN disclosed
CN-118063658-A Polybutene-1 and process for preparing same 中国科学院化学研究所 2024-05-24 CN disclosed
CN-112142895-B Application of organosilane, random copolymer polypropylene and preparation method thereof 中国科学院化学研究所 2024-03-22 CN disclosed
CN-116199813-A Long chain branched polypropylene and preparation method thereof 中国科学院化学研究所 2023-06-02 CN disclosed
CN-112142894-A Application of organosilane in preparation of high-density polyethylene, high-density polyethylene and preparation method and application thereof 中国科学院化学研究所 2020-12-29 CN disclosed
CN-112142895-A Application of organosilane, random copolymerization polypropylene and preparation method thereof 中国科学院化学研究所 2020-12-29 CN disclosed
CN-108659151-B Application of organosilane, polypropylene and preparation method of polypropylene 中国科学院化学研究所 2020-01-10 CN disclosed
US-5985462-A COATINGS, RELEASE AGENTS; HYDROSILATION; CATALYSIS WACKER-CHEMIE GMBH (DE) 1999-11-16 US disclosed