Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8437291 | 0.78 | TSHR (0.39) | TSHRALDH1A1MAPTUSP2CYP3A4 | |
| SCHEMBL6037393 | 0.77 | TSHR (0.43) | TSHRALDH1A1MAPTUSP2CYP3A4 | |
| SCHEMBL28350398 | 0.77 | TSHR (0.43) | TSHRALDH1A1MAPTUSP2CYP3A4 | |
| SCHEMBL28492067 | 0.77 | TSHR (0.43) | TSHRALDH1A1MAPTUSP2CYP3A4 | |
| SCHEMBL28491282 | 0.77 | TSHR (0.43) | TSHRALDH1A1MAPTUSP2CYP3A4 | |
| SCHEMBL5523530 | 0.77 | TSHR (0.38) | TSHRALDH1A1MAPTUSP2CYP3A4 | |
| SCHEMBL6037376 | 0.75 | TSHR (0.41) | TSHRALDH1A1MAPTUSP2CYP3A4 | |
| SCHEMBL313009 | 0.75 | — | — | |
| SCHEMBL1760678 | 0.74 | — | — | |
| SCHEMBL22493527 | 0.73 | TSHR (0.48) | TSHRALDH1A1MAPTUSP2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866707-A | Process for preparing organosilicon compounds having Si-bonded hydrogen atoms | WACKER-CHEMIE GMBH (DE) | 1999-02-02 | — | — | US | disclosed |