SCHEMBL8437337

SCHEMBL8437337

CC=C(C)C(=O)NCCCN(C)C

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.54
DNM1 Q05193 1/20 0.46
PAOX Q6QHF9 1/20 0.44
LMNA P02545 1/20 0.44
ALDH1A1 P00352 2/20 0.41
MEN1 O00255 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.39
POLB P06746 1/20 0.39
P2RX4 Q99571 1/20 0.38
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17165990 0.86 KDM4E (0.59) KDM4EDNM1PAOXLMNAALDH1A1
SCHEMBL13464622 0.83 KDM4E (0.44) KDM4EPAOXALDH1A1MEN1KMT2A
SCHEMBL78355 0.83 KDM4E (0.59) KDM4EDNM1PAOXLMNAALDH1A1
SCHEMBL15834749 0.82 KDM4E (0.49) KDM4EDNM1PAOXLMNAALDH1A1
SCHEMBL28253085 0.82 L3MBTL1 (0.40) KDM4EPOLB
SCHEMBL6422467 0.81 KDM4E (0.48) KDM4EDNM1PAOXLMNAALDH1A1
SCHEMBL18141083 0.81 KDM4E (0.51) KDM4EDNM1PAOXLMNAALDH1A1
SCHEMBL23196731 0.80 TDP1 (0.43) KDM4EPAOXMEN1KMT2APOLB
SCHEMBL28866044 0.80 TDP1 (0.43) KDM4EPAOXMEN1KMT2APOLB
SCHEMBL21954 0.78 KDM4E (0.56) KDM4EDNM1PAOXLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117203007-A Composition comprising silver nanoplates 巴斯夫欧洲公司 2023-12-08 CN disclosed
EP-0602235-B1 AQUEOUS LIQUID FOR PRIMERS NAT STARCH CHEM INVEST (US) 1999-12-15 EP disclosed
US-5455299-A Cationic monomer, alkoxysilane containing monomer, ethylenic unsaturated monomer; storage stability NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1995-10-03 US disclosed
EP-0602235-A1 AQUEOUS LIQUID FOR PRIMERS National Starch and Chemical Investment Holding Corporation (US) 1994-06-22 EP disclosed
WO-1994000520-A1 AQUEOUS LIQUID FOR PRIMERS NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1994-01-06 WO disclosed