Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8305094 | 0.85 | SNCA (0.43) | SNCAKMT2AMEN1CYP3A4ALDH1A1 | |
| SCHEMBL8442811 | 0.83 | SNCA (0.37) | SNCAKMT2AMEN1CYP3A4ALDH1A1 | |
| SCHEMBL8593228 | 0.83 | SNCA (0.37) | SNCAKMT2AMEN1CYP3A4ALDH1A1 | |
| SCHEMBL8596008 | 0.83 | SNCA (0.37) | SNCAKMT2AMEN1CYP3A4ALDH1A1 | |
| SCHEMBL8305671 | 0.83 | SNCA (0.38) | SNCAKMT2AMEN1CYP3A4ALDH1A1 | |
| SCHEMBL8299788 | 0.83 | SNCA (0.38) | SNCAKMT2AMEN1CYP3A4ALDH1A1 | |
| SCHEMBL8652713 | 0.80 | EPHX1 (0.36) | SNCAKMT2AMEN1ALDH1A1ADRB2 | |
| SCHEMBL8720293 | 0.80 | SNCA (0.36) | SNCAKMT2AMEN1CYP3A4ALDH1A1 | |
| SCHEMBL8300761 | 0.77 | SNCA (0.42) | SNCAKMT2AMEN1CYP3A4ALDH1A1 | |
| Allyl Alcohol SCHEMBL8437400 | 0.74 | SNCA (0.40) | SNCAKMT2AMEN1CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915843-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSES | SMITHKLINE BEECHAM PLC (GB) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997041098-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-11-06 | — | — | WO | disclosed |