Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.62 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.62 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.62 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8437536 | 1.00 | LMNA (0.66) | LMNACYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL8437532 | 1.00 | LMNA (0.66) | LMNACYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL19865603 | 0.87 | MAPK1 (0.60) | LMNACYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL267463 | 0.83 | LMNA (0.68) | LMNACYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL13263721 | 0.83 | USP2 (0.58) | LMNACYP2D6KDM4EMEN1ALDH1A1 | |
| SCHEMBL16885283 | 0.83 | POLB (0.54) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL19865604 | 0.81 | MAPK1 (0.54) | LMNACYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL18568523 | 0.80 | LMNA (0.59) | LMNACYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL166337 | 0.80 | LMNA (0.64) | LMNACYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL16448411 | 0.80 | LMNA (0.54) | LMNACYP2D6ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022047375-A1 | NOVEL FUNGAL MODULATORS | TRUSTEES OF BOSTON UNIVERSITY (US) | 2022-03-03 | — | — | WO | disclosed |
| US-5977409-A | Method of using α-substituted benzylamine chiral auxiliary synthetic reagents | UNIVERSITY OF TOLEDO (US) | 1999-11-02 | — | — | US | disclosed |