Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 9/20 | 0.33 |
| ▸ | CNR1 | P21554 | 8/20 | 0.33 |
| ▸ | NQO1 | P15559 | 3/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7402484 | 0.90 | CNR1 (0.34) | KDM4EMAPTGAAJAK2POLB | |
| SCHEMBL7407490 | 0.88 | KDM4E (0.35) | KDM4EMAPTGAAJAK2POLB | |
| SCHEMBL8434645 | 0.83 | NR3C1 (0.32) | KDM4EMAPTGAAJAK2POLB | |
| SCHEMBL7405496 | 0.82 | CNR2 (0.35) | KDM4EMAPTGAAJAK2POLB | |
| SCHEMBL7376729 | 0.81 | NR3C1 (0.33) | KDM4EMAPTGAAJAK2POLB | |
| SCHEMBL6177242 | 0.74 | TYR (0.35) | KDM4EMAPTGAAJAK2POLB | |
| SCHEMBL6175176 | 0.73 | SLC6A2 (0.31) | CNR1NQO1 | |
| SCHEMBL6174971 | 0.72 | NQO1 (0.31) | NQO1HSD17B3ESR1AR | |
| SCHEMBL7371322 | 0.72 | CYP2C9 (0.34) | — | |
| SCHEMBL6174864 | 0.71 | NQO1 (0.32) | MAPTNQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6005103-A | TREATMENT OF BACTERIAL AND VIRAL INFECTIONS AND DISEASES, INCLUDING AIDS | WARNER-LAMBERT COMPANY (US) | 1999-12-21 | — | — | US | disclosed |
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |