Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 2/20 | 0.35 |
| ▸ | DNTT | P04053 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 2/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.30 |
| ▸ | TACR2 | P21452 | 2/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8436810 | 1.00 | POLA1 (0.35) | POLA1DNTTPOLBPTPN1OPRM1 | |
| SCHEMBL5803999 | 1.00 | POLA1 (0.35) | POLA1DNTTPOLBPTPN1OPRM1 | |
| SCHEMBL8433691 | 1.00 | POLA1 (0.35) | POLA1DNTTPOLBPTPN1OPRM1 | |
| SCHEMBL27389195 | 0.86 | — | — | |
| SCHEMBL11415772 | 0.82 | DNTT (0.34) | POLA1DNTTPOLBOPRM1OPRD1 | |
| SCHEMBL27885764 | 0.82 | DNTT (0.34) | POLA1DNTTPOLBOPRM1OPRD1 | |
| SCHEMBL10450060 | 0.82 | DNTT (0.34) | POLA1DNTTPOLBOPRM1OPRD1 | |
| SCHEMBL28888351 | 0.80 | DNTT (0.32) | POLA1DNTTPOLBGAACNR1 | |
| SCHEMBL31279666 | 0.80 | DNTT (0.32) | POLA1DNTTPOLBGAACNR1 | |
| SCHEMBL11520528 | 0.80 | DNTT (0.32) | POLA1DNTTPOLBGAACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36139-E | ANTIOXIDANTS FOR FOODS, COSMETICS; ANTITUMOR AGENTS | NIPPON HYPOX LABORATORIES INCORPORATED (JP) | 1999-03-09 | — | — | US | disclosed |
| US-5416242-A | Compounds for oxidation resistance | NIPPON HYPOX LABORATORIES INCORPORATED (JP) | 1995-05-16 | — | — | US | disclosed |
| EP-0589069-A1 | Hydroquinone derivatives and antioxidants and tumor inhibitors containing them | NIPPON HYPOX LABORATORIES INCORPORATED (JP) | 1994-03-30 | — | — | EP | disclosed |