Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNTT | P04053 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | POLA1 | P09884 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.30 |
| ▸ | ESR1 | P03372 | 2/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.30 |
| ▸ | TACR2 | P21452 | 2/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SHBG | P04278 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31279666 | 1.00 | DNTT (0.32) | DNTTPOLBPOLA1GAACNR1 | |
| SCHEMBL4632343 | 0.86 | — | — | |
| SCHEMBL8436810 | 0.80 | POLA1 (0.35) | DNTTPOLBPOLA1GAACNR1 | |
| SCHEMBL5803999 | 0.80 | POLA1 (0.35) | DNTTPOLBPOLA1GAACNR1 | |
| SCHEMBL8437732 | 0.80 | POLA1 (0.35) | DNTTPOLBPOLA1GAACNR1 | |
| SCHEMBL25330339 | 0.77 | DNTT (0.32) | DNTTPOLBPOLA1 | |
| SCHEMBL28195813 | 0.74 | — | — | |
| SCHEMBL27970678 | 0.72 | — | — | |
| SCHEMBL13674566 | 0.72 | S1PR1 (0.47) | CYP3A4 | |
| SCHEMBL9313668 | 0.71 | GAA (0.33) | DNTTPOLBPOLA1GAAPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4163670-A | PYRAZOLONE COUPLERS | FUJI PHOTO FILM CO., LTD. (JP) | 1979-08-07 | — | — | US | disclosed |