Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 14/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL843529 | 1.00 | CHRNA7 (0.52) | CHRNA7RAB9AHTR3ANPC1KMT2A | |
| SCHEMBL843528 | 1.00 | CHRNA7 (0.52) | CHRNA7RAB9AHTR3ANPC1KMT2A | |
| SCHEMBL843652 | 0.95 | CHRNA7 (0.45) | CHRNA7RAB9AHTR3A | |
| SCHEMBL842326 | 0.83 | CHRNA7 (0.59) | CHRNA7HTR3A | |
| SCHEMBL6008657 | 0.81 | CHRNA7 (0.65) | CHRNA7HTR3A | |
| SCHEMBL6008770 | 0.81 | CHRNA7 (0.65) | CHRNA7HTR3A | |
| Hydrochloric Acid SCHEMBL6008611 | 0.80 | CHRNA7 (0.64) | CHRNA7HTR3A | |
| SCHEMBL6100386 | 0.77 | HTR3A (0.67) | CHRNA7HTR3A | |
| SCHEMBL6100380 | 0.77 | HTR3A (0.67) | CHRNA7HTR3A | |
| SCHEMBL842945 | 0.77 | CHRNA7 (0.58) | CHRNA7RAB9AHTR3ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432707-B1 | AZABICYCLIC-SUBSTITUTED FUSED-HETEROARYL COMPOUNDS FOR THE TREATMENT OF DISEASE | PHARMACIA & UPJOHN CO LLC (US) | 2012-03-28 | — | — | EP | disclosed |