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Triphosphate

Triphosphate

SCHEMBL8437845

CC(C)=CCC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CNc1cc[nH]c(=O)n1.O=P(O)(O)OP(=O)(O)OP(=O)(O)O

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ FNTA P49354 13/20 0.48
▸ FNTB P49356 11/20 0.48
▸ PGGT1B P53609 6/20 0.48
▸ GGPS1 O95749 4/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triphosphate SCHEMBL8436500 1.00 FNTA (0.48) FNTAFNTBPGGT1BGGPS1
Triphosphate SCHEMBL8440665 0.99 FNTA (0.46) FNTAFNTBPGGT1BGGPS1
Triphosphate SCHEMBL8441475 0.87 FNTA (0.32) FNTAFNTBPGGT1B
Triphosphate SCHEMBL8439930 0.81 FNTA (0.35) FNTAFNTBPGGT1BGGPS1
Triphosphate SCHEMBL8438673 0.79 HCAR3 (0.35) —
Triphosphate SCHEMBL8441046 0.77 P2RY2 (0.35) —
Triphosphate SCHEMBL8436875 0.76 BTN3A1 (0.40) —
Triphosphate SCHEMBL8440660 0.75 P2RY2 (0.40) —
Triphosphate SCHEMBL8435664 0.73 P2RY2 (0.45) —
Triphosphate SCHEMBL7818664 0.73 P2RY2 (0.35) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5902793-A ADMINISTERING TO MAMMAL GAMMA-MONOALKYL- OR GAMMA-ALKENYL-NUCLEOSIDE OR DEOXYNUCLEOSIDE TRIPHOSPHATE ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) 1999-05-11 — — US claimed
US-5902793-A ADMINISTERING TO MAMMAL GAMMA-MONOALKYL- OR GAMMA-ALKENYL-NUCLEOSIDE OR DEOXYNUCLEOSIDE TRIPHOSPHATE ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) 1999-05-11 — — US disclosed
US-5639653-A ADMINISTERING MONOALKYL- OR ALKENYL-PYROPHOSPHATE TO MAMMAL TO STIMULATE LYMPHOCYTE CELL GROWTH AND ENHANCE IMMUNE RESPONSE ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY, A DIVISION OF YESHIVA UNIVERSTIY (US) 1997-06-17 — — US disclosed