SCHEMBL8437853

SCHEMBL8437853

CCCCC(CCCC)n1c(=O)sc2c(=O)[nH]c(N)nc21

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 19/20 0.47
PNP P00491 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8440477 0.96 TLR7 (0.46) TLR7PNP
SCHEMBL8440057 0.87 TLR7 (0.50) TLR7
SCHEMBL9257251 0.80 TLR7 (0.48) TLR7
SCHEMBL22911735 0.77 TLR7 (0.53) TLR7
SCHEMBL338431 0.75 PNP (0.61) TLR7PNP
SCHEMBL13851087 0.74 HPGD (0.51) TLR7PNP
SCHEMBL18871227 0.73 PNP (0.49) PNP
SCHEMBL67181 0.71 TLR7 (0.46) TLR7
SCHEMBL22911737 0.71 TLR7 (0.46) TLR7
SCHEMBL19335107 0.70 PNP (0.54) PNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5994321-A Antiviral guanine analogs ARONEX PHARMACEUTICALS, INC. (US) 1999-11-30 US disclosed