Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 18/20 | 0.46 |
| ▸ | PNP | P00491 | 1/20 | 0.43 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8437853 | 0.96 | TLR7 (0.47) | TLR7PNP | |
| SCHEMBL8440057 | 0.85 | TLR7 (0.50) | TLR7 | |
| SCHEMBL338431 | 0.77 | PNP (0.61) | TLR7PNP | |
| SCHEMBL22911735 | 0.76 | TLR7 (0.53) | TLR7 | |
| SCHEMBL19335107 | 0.74 | PNP (0.54) | PNP | |
| SCHEMBL21283065 | 0.73 | PNP (0.53) | PNP | |
| SCHEMBL13851087 | 0.73 | HPGD (0.51) | TLR7PNP | |
| SCHEMBL67181 | 0.70 | TLR7 (0.46) | TLR7 | |
| SCHEMBL22911737 | 0.70 | TLR7 (0.46) | TLR7 | |
| SCHEMBL18871227 | 0.70 | PNP (0.49) | PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994321-A | Antiviral guanine analogs | ARONEX PHARMACEUTICALS, INC. (US) | 1999-11-30 | — | — | US | disclosed |
| US-5446045-A | Viricides for treating AIDS, viral diseases | TRIPLEX PHARMACEUTICAL CORPORATION | 1995-08-29 | — | — | US | disclosed |