Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 6/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 6/20 | 0.40 |
| ▸ | MMP3 | P08254 | 5/20 | 0.40 |
| ▸ | IDH1 | O75874 | 5/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | IL6ST | P40189 | 1/20 | 0.37 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | FCER2 | P06734 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7088311 | 1.00 | MMP2 (0.44) | MMP2MMP9MMP12PPARAMMP1 | |
| SCHEMBL8438051 | 1.00 | MMP2 (0.44) | MMP2MMP9MMP12PPARAMMP1 | |
| SCHEMBL7088313 | 1.00 | MMP2 (0.44) | MMP2MMP9MMP12PPARAMMP1 | |
| SCHEMBL19819289 | 0.99 | MMP2 (0.43) | MMP2MMP9MMP12PPARAMMP1 | |
| SCHEMBL19819288 | 0.99 | MMP2 (0.43) | MMP2MMP9MMP12PPARAMMP1 | |
| SCHEMBL19819290 | 0.99 | MMP2 (0.43) | MMP2MMP9MMP12PPARAMMP1 | |
| SCHEMBL1190273 | 0.90 | PPARA (0.42) | PPARAIDH1ATMIL6STNAAA | |
| SCHEMBL3020671 | 0.90 | PPARA (0.39) | MMP2MMP9MMP12PPARAIDH1 | |
| SCHEMBL3020667 | 0.90 | PPARA (0.39) | MMP2MMP9MMP12PPARAIDH1 | |
| SCHEMBL19815463 | 0.89 | PPARA (0.41) | PPARAIDH1ATMIL6STNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952507-A | Process for manufacture of chiral succinic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1999-09-14 | — | — | US | disclosed |