SCHEMBL8438348

SCHEMBL8438348

[Li]C(OCC)C(CC)OC

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.39
THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12514138 0.76 LMNA (0.45) LMNATHRB
SCHEMBL18493329 0.72 LMNA (0.48) LMNATHRB
SCHEMBL8439549 0.72
SCHEMBL10309515 0.71 LMNA (0.33) LMNA
SCHEMBL13672319 0.71 LMNA (0.33) LMNA
SCHEMBL11289846 0.70 LMNA (0.39) LMNATHRB
SCHEMBL8433446 0.70 LMNA (0.39) LMNATHRB
SCHEMBL11915408 0.69
SCHEMBL2778431 0.69
SCHEMBL27471022 0.68 LMNA (0.56) LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5900464-A USING AN ORGANOMETALLIC COMPOUND AS PROMOTER FMC CORPORATION (US) 1999-05-04 US claimed
US-5849847-A Telechelic polystyrene/polyethylene copolymers and processes for making same FMC CORPORATION (US) 1998-12-15 US claimed
US-5922810-A EFFECTIVE DEBLOCKING A TELECHELIC STAR POLYMER WITH AN ACID CATALYST FMC CORPORATION (US) 1999-07-13 US disclosed
US-5900464-A USING AN ORGANOMETALLIC COMPOUND AS PROMOTER FMC CORPORATION (US) 1999-05-04 US disclosed
US-5849847-A Telechelic polystyrene/polyethylene copolymers and processes for making same FMC CORPORATION (US) 1998-12-15 US disclosed
US-5827929-A Functionalized initiators for anionic polymerization FMC CORPORATION (US) 1998-10-27 US disclosed
US-5821307-A Functionalized chain extended initiators for anionic polymerization FMC CORPORATION (US) 1998-10-13 US disclosed
US-5708092-A Functionalized chain extended initiators for anionic polymerization FMC CORPORATION (US) 1998-01-13 US disclosed