Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | SCN1A | P35498 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethenamid SCHEMBL5087814 | 0.88 | THRB (1.00) | THRBALDH1A1TP53CYP3A4LMNA | |
| Dimethenamid SCHEMBL18223 | 0.88 | THRB (1.00) | THRBALDH1A1TP53CYP3A4LMNA | |
| Dimethenamid SCHEMBL53864 | 0.88 | THRB (1.00) | THRBALDH1A1TP53CYP3A4LMNA | |
| Dimethenamid SCHEMBL20723471 | 0.87 | THRB (0.97) | THRBALDH1A1TP53CYP3A4LMNA | |
| Dimethenamid SCHEMBL20723446 | 0.87 | THRB (0.97) | THRBALDH1A1TP53CYP3A4LMNA | |
| SCHEMBL9155572 | 0.84 | THRB (0.74) | THRBALDH1A1TP53LMNASMN1; SMN2 | |
| Dimethenamid SCHEMBL28212854 | 0.83 | THRB (0.88) | THRBALDH1A1TP53LMNASMN1; SMN2 | |
| SCHEMBL11569945 | 0.81 | TP53 (0.54) | THRBALDH1A1TP53CYP3A4TDP1 | |
| SCHEMBL10715783 | 0.80 | THRB (0.72) | THRBALDH1A1TP53CYP3A4TDP1 | |
| Metolachor SCHEMBL17927060 | 0.80 | THRB (0.78) | THRBALDH1A1TP53CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646315-B1 | Novel compositions containing an auxin transport inhibitor and another herbicide | NOVARTIS AG (CH) | 1999-05-12 | — | — | EP | claimed |
| EP-0646315-B1 | Novel compositions containing an auxin transport inhibitor and another herbicide | NOVARTIS AG (CH) | 1999-05-12 | — | — | EP | disclosed |
| EP-0646315-A1 | Novel compositions containing an auxin transport inhibitor and another herbicide | SANDOZ LTD. (CH) | 1995-04-05 | — | — | EP | disclosed |