Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.37 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8436013 | 1.00 | ALDH1A1 (0.41) | ALDH1A1GAAMAPK1L3MBTL1GRIN2B | |
| SCHEMBL8438096 | 0.93 | ALDH1A1 (0.44) | ALDH1A1GAAMAPK1L3MBTL1GRIN2B | |
| SCHEMBL8438094 | 0.93 | ALDH1A1 (0.44) | ALDH1A1GAAMAPK1L3MBTL1GRIN2B | |
| SCHEMBL8435165 | 0.90 | ALDH1A1 (0.43) | ALDH1A1GAAMAPK1L3MBTL1GRIN2B | |
| SCHEMBL8435168 | 0.90 | ALDH1A1 (0.43) | ALDH1A1GAAMAPK1L3MBTL1GRIN2B | |
| Hydrochloric Acid SCHEMBL8435926 | 0.88 | GAA (0.38) | ALDH1A1GAAMAPK1L3MBTL1GRIN2B | |
| Hydrochloric Acid SCHEMBL8439146 | 0.88 | GAA (0.38) | ALDH1A1GAAMAPK1L3MBTL1GRIN2B | |
| Hydrochloric Acid SCHEMBL8435924 | 0.88 | GAA (0.38) | ALDH1A1GAAMAPK1L3MBTL1GRIN2B | |
| SCHEMBL9125555 | 0.88 | ALDH1A1 (0.44) | ALDH1A1GAAMAPK1L3MBTL1GRIN2B | |
| SCHEMBL7458116 | 0.88 | ALDH1A1 (0.42) | ALDH1A1GAAMAPK1L3MBTL1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0560613-A1 | Antimicrobial carbapenem derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1993-09-15 | — | — | EP | disclosed |