Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6233242 | 0.83 | TSHR (0.56) | GLAL3MBTL1POLBTSHRLMNA | |
| SCHEMBL20520314 | 0.82 | GLA (0.64) | GLAL3MBTL1POLBTSHRLMNA | |
| Hydrochloric Acid SCHEMBL30405920 | 0.82 | POLB (0.54) | GLAL3MBTL1POLBTSHRLMNA | |
| SCHEMBL14079952 | 0.81 | TSHR (0.54) | GLAL3MBTL1POLBTSHRLMNA | |
| SCHEMBL8789603 | 0.80 | GLA (0.50) | GLAL3MBTL1POLBTSHRLMNA | |
| SCHEMBL8333937 | 0.79 | KDM4E (0.52) | GLAL3MBTL1TSHRLMNAKDM4E | |
| SCHEMBL3466247 | 0.77 | L3MBTL1 (0.55) | GLAL3MBTL1POLBTSHRLMNA | |
| SCHEMBL21003902 | 0.77 | GLA (0.50) | GLAL3MBTL1POLBTSHRLMNA | |
| SCHEMBL16638643 | 0.77 | PAOX (0.64) | GLATSHRLMNAALDH1A1KDM4E | |
| SCHEMBL7385455 | 0.77 | GLA (0.57) | GLAL3MBTL1POLBTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5863949-A | Arylsulfonylamino hydroxamic acid derivatives | PFIZER INC (US) | 1999-01-26 | — | — | US | disclosed |