Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 3/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 4/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2040683 | 0.89 | ADRA1A (0.46) | ADRA1AHPGDSADRA2AADRA1DADRA1B | |
| SCHEMBL1299321 | 0.88 | ADRA1A (0.52) | ADRA1AHPGDSADRA2AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL9986840 | 0.87 | ADRA1A (0.45) | ADRA1AHPGDSADRA2AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL7417858 | 0.86 | ADRA1A (0.50) | ADRA1AHPGDSADRA2AADRA1DADRA1B | |
| Bromide SCHEMBL9220604 | 0.86 | ADRA1A (0.50) | ADRA1AHPGDSADRA2AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL2517321 | 0.86 | ADRA1A (0.50) | ADRA1AHPGDSADRA2AADRA1DADRA1B | |
| SCHEMBL1299173 | 0.84 | — | — | |
| SCHEMBL196337 | 0.79 | — | — | |
| SCHEMBL1494449 | 0.75 | — | — | |
| SCHEMBL184451 | 0.75 | ADRA1A (0.55) | ADRA1AADRA2AADRA1DADRA1BHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0560613-A1 | Antimicrobial carbapenem derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1993-09-15 | — | — | EP | disclosed |