Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 16/20 | 0.64 |
| ▸ | CNR1 | P21554 | 8/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL843288 | 0.89 | CNR2 (0.66) | CNR2CNR1TYRBRD4 | |
| SCHEMBL843701 | 0.88 | CNR2 (0.63) | CNR2CNR1BRD4 | |
| SCHEMBL9897579 | 0.80 | CNR2 (0.71) | CNR2CNR1 | |
| SCHEMBL9897576 | 0.79 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL843936 | 0.76 | CNR2 (0.64) | CNR2CNR1BRD4 | |
| SCHEMBL29868051 | 0.74 | TYR (0.44) | CNR2TYR | |
| SCHEMBL28346478 | 0.69 | CNR2 (0.43) | CNR2CNR1BRD4 | |
| SCHEMBL859363 | 0.68 | CNR2 (0.71) | CNR2CNR1BRD4 | |
| SCHEMBL29812644 | 0.67 | MAP2K1 (0.41) | TYRBRD4 | |
| SCHEMBL859362 | 0.67 | CNR2 (1.00) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432763-A1 | 1,4 DIHYDROPYRIDINE DERIVATIVES AND THEIR USES | Université de Lille 2 Droit et Santé (FR) | 2012-03-28 | — | — | EP | claimed |
| WO-2010133973-A1 | 1,4 DIHYDROPYRIDINE DERIVATIVES AND THEIR USES | UNIVERSITE LILLE 2 DROIT ET SANTE (FR) | 2010-11-25 | — | — | WO | claimed |