Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8522168 | 0.92 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL7890351 | 0.91 | AGTR1 (0.60) | AGTR1AGTR2 | |
| SCHEMBL8435232 | 0.90 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL9204574 | 0.89 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL8434213 | 0.87 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL8433706 | 0.86 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL8438466 | 0.85 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL1256316 | 0.84 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL8586238 | 0.84 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL946900 | 0.83 | AGTR1 (0.67) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0427463-B1 | Substituted N-(imidazolyl)alkyl alanine derivatives | SMITHKLINE BEECHAM CORP (US) | 1995-03-08 | — | — | EP | claimed |
| EP-0427463-A1 | Substituted N-(imidazolyl)alkyl alanine derivatives | SMITHKLINE BEECHAM CORPORATION (US) | 1991-05-15 | — | — | EP | claimed |
| US-5929249-A | ANGIOTENSIN II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-07-27 | — | — | US | disclosed |
| US-5728842-A | ANGIOTENSIN II RECEPTOR ANTAGONIST | SMITHKLINE BEECHAM CORPORATION (US) | 1998-03-17 | — | — | US | disclosed |
| WO-1994000120-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-01-06 | — | — | WO | disclosed |
| WO-1993006828-A1 | MEDICAMENT FOR THE TREATMENT OF ANXIETY | SMITHKLINE BEECHAM CORPORATION (US) | 1993-04-15 | — | — | WO | disclosed |