Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441070 | 0.93 | — | — | |
| SCHEMBL8436062 | 0.86 | CES2 (0.30) | CES2GMNNTP53POLBMAPT | |
| SCHEMBL8437055 | 0.85 | — | — | |
| SCHEMBL8437368 | 0.84 | CES2 (0.32) | CES2GMNNTP53POLBMAPT | |
| SCHEMBL8441362 | 0.83 | — | — | |
| SCHEMBL8439907 | 0.81 | — | — | |
| SCHEMBL8441313 | 0.81 | MEN1 (0.32) | CES2MAPTTHRBBLM | |
| SCHEMBL8439963 | 0.81 | MEN1 (0.32) | CES2MAPTTHRBBLM | |
| SCHEMBL8439863 | 0.79 | — | — | |
| SCHEMBL8440029 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5912374-A | Asymmetrical siloxy compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-06-15 | — | — | US | disclosed |
| EP-0794187-A1 | Asymmetrical siloxy compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-09-10 | — | — | EP | disclosed |