Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 12/20 | 0.57 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441675 | 0.90 | HTR1A (0.59) | HTR1ACHRNA7HTR3ATRPA1SLC6A4 | |
| SCHEMBL8439326 | 0.84 | HTR1A (0.58) | HTR1ASLC6A4OPRM1 | |
| SCHEMBL8440473 | 0.82 | HTR1A (0.43) | HTR1ASLC6A4 | |
| SCHEMBL8440360 | 0.81 | HTR1A (0.57) | HTR1ASLC6A4 | |
| SCHEMBL8440023 | 0.77 | HTR1A (0.48) | HTR1ACHRNA7HTR3A | |
| SCHEMBL8441075 | 0.76 | HTR1A (0.57) | HTR1A | |
| SCHEMBL8439530 | 0.74 | HTR1A (0.57) | HTR1ASLC6A4 | |
| SCHEMBL8442405 | 0.73 | FASN (0.40) | HTR1ATRPA1SLC6A4SRD5A1OPRM1 | |
| SCHEMBL6975848 | 0.73 | HTR1A (1.00) | HTR1A | |
| SCHEMBL6975844 | 0.73 | HTR1A (1.00) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958927-A | PSYCHOLOGICAL AND NERVOUS SYSTEM DISORDERS | ADIR ET COMPAGNIE (FR) | 1999-09-28 | — | — | US | disclosed |