Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | TYMP | P19971 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 9/20 | 0.39 |
| ▸ | MPEG1 | Q2M385 | 7/20 | 0.39 |
| ▸ | CDC25A | P30304 | 6/20 | 0.39 |
| ▸ | CDC25B | P30305 | 6/20 | 0.39 |
| ▸ | CDC25C | P30307 | 5/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.39 |
| ▸ | XIAP | P98170 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5970520 | 1.00 | ALDH1A1 (0.51) | ALDH1A1MAPTTDP1THRBTYMP | |
| SCHEMBL187581 | 1.00 | ALDH1A1 (0.51) | ALDH1A1MAPTTDP1THRBTYMP | |
| SCHEMBL5722122 | 1.00 | ALDH1A1 (0.51) | ALDH1A1MAPTTDP1THRBTYMP | |
| SCHEMBL8438882 | 1.00 | ALDH1A1 (0.51) | ALDH1A1MAPTTDP1THRBTYMP | |
| SCHEMBL4654368 | 1.00 | ALDH1A1 (0.51) | ALDH1A1MAPTTDP1THRBTYMP | |
| SCHEMBL27611153 | 1.00 | ALDH1A1 (0.51) | ALDH1A1MAPTTDP1THRBTYMP | |
| SCHEMBL1535496 | 0.98 | ALDH1A1 (0.49) | ALDH1A1MAPTTDP1THRBTYMP | |
| SCHEMBL1535486 | 0.92 | ALDH1A1 (0.42) | ALDH1A1MAPTTDP1THRBTYMP | |
| SCHEMBL8442749 | 0.92 | MAPT (0.40) | ALDH1A1MAPTTDP1THRBCDC25B | |
| SCHEMBL8443084 | 0.92 | MAPT (0.40) | ALDH1A1MAPTTDP1THRBCDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0495544-B1 | Process for the synthesis of citraconimides | AKZO NOBEL NV (NL) | 1999-04-07 | — | — | EP | disclosed |
| US-5523360-A | IMPROVES MELT-FLOW PROPERTIES | AKZO NOBEL N. V. (NL) | 1996-06-04 | — | — | US | disclosed |
| EP-0648240-A1 | PROCESS FOR THE MODIFICATION OF POLYPHENYLENE ETHER RESIN COMPOSITIONS | Akzo Nobel N.V. (NL) | 1995-04-19 | — | — | EP | disclosed |
| WO-1994001485-A1 | PROCESS FOR THE MODIFICATION OF POLYPHENYLENE ETHER RESIN COMPOSITIONS | AKZO NOBEL N.V. (NL) | 1994-01-20 | — | — | WO | disclosed |