SCHEMBL8439729

SCHEMBL8439729

N#Cc1cc(NCCO)ccc1[N+](=O)[O-]

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.54
ALDH1A1 P00352 4/20 0.45
TDP1 Q9NUW8 2/20 0.45
TSHR P16473 1/20 0.45
VCAM1 P19320 1/20 0.41
MAPT P10636 7/20 0.41
GLA P06280 1/20 0.40
GAA P10253 1/20 0.40
HTR6 P50406 1/20 0.40
GRIA1 P42261 2/20 0.39
GRIA2 P42262 2/20 0.39
GRIA3 P42263 2/20 0.39
GRIA4 P48058 2/20 0.39
GRM6 O15303 1/20 0.39
CYP1A2 P05177 1/20 0.39
ALOX15 P16050 1/20 0.39
RECQL P46063 1/20 0.39
POLB P06746 2/20 0.39
HPGD P15428 2/20 0.38
CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9799360 0.86 HCAR3 (0.43) RAB9AALDH1A1TDP1VCAM1MAPT
SCHEMBL9798733 0.83 MAPT (0.49) ALDH1A1TDP1VCAM1MAPTGLA
SCHEMBL5278995 0.83 SMN1; SMN2 (0.48) RAB9AALDH1A1VCAM1MAPTGLA
SCHEMBL9586447 0.82 MAPT (0.50) RAB9AALDH1A1TDP1VCAM1MAPT
SCHEMBL9798797 0.82 HCAR3 (0.46) RAB9AALDH1A1TDP1VCAM1MAPT
SCHEMBL8436247 0.81 GLA (0.54) RAB9ATDP1VCAM1MAPTGLA
SCHEMBL9798855 0.81 HCAR3 (0.45) ALDH1A1TDP1VCAM1MAPTGLA
SCHEMBL9798791 0.81 HCAR3 (0.45) ALDH1A1TDP1VCAM1MAPTGLA
SCHEMBL9798470 0.81 HCAR3 (0.45) ALDH1A1TDP1VCAM1MAPTGLA
SCHEMBL9798673 0.81 HCAR3 (0.45) ALDH1A1TDP1VCAM1MAPTGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5865856-A MIXTURE CONTAINING COUPLER AND DEVELOPER WELLA AKTIENGESELLSCHAFT (DE) 1999-02-02 US disclosed
EP-0797980-A1 Oxidation hair dye composition comprising a 2,5-diaminobenzonitrile as well as 2,5-diaminobenzonitrile compounds Wella Aktiengesellschaft (DE) 1997-10-01 EP disclosed