Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5694217 | 1.00 | ALDH1A1 (0.56) | ALDH1A1LMNAAPOBEC3AAPOBEC3GTSHR | |
| SCHEMBL10845203 | 1.00 | ALDH1A1 (0.56) | ALDH1A1LMNAAPOBEC3AAPOBEC3GTSHR | |
| SCHEMBL9533237 | 1.00 | ALDH1A1 (0.56) | ALDH1A1LMNAAPOBEC3AAPOBEC3GTSHR | |
| SCHEMBL1532527 | 1.00 | ALDH1A1 (0.56) | ALDH1A1LMNAAPOBEC3AAPOBEC3GTSHR | |
| SCHEMBL4987219 | 1.00 | ALDH1A1 (0.56) | ALDH1A1LMNAAPOBEC3AAPOBEC3GTSHR | |
| SCHEMBL14673470 | 1.00 | ALDH1A1 (0.56) | ALDH1A1LMNAAPOBEC3AAPOBEC3GTSHR | |
| SCHEMBL1270067 | 0.98 | — | — | |
| SCHEMBL408956 | 0.90 | — | — | |
| Phosphine SCHEMBL10880551 | 0.88 | — | — | |
| SCHEMBL4441760 | 0.87 | ALDH1A1 (0.70) | ALDH1A1LMNAAPOBEC3AAPOBEC3GTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101333158-B | Method for preparing idebenone | Suzhou lixin pharmaceutical co ltd | 2010-07-21 | — | — | CN | disclosed |
| CN-101333158-A | Method for preparing idebenone | SUZHOU LIXIN PHARMACEUTICAL CO (CN) | 2008-12-31 | — | — | CN | disclosed |
| EP-0675130-B1 | Process for the preparation of phosphonium salts | SHINETSU CHEMICAL CO (JP) | 1999-12-29 | — | — | EP | disclosed |
| US-5481040-A | REACTING A PHOSPHINE WITH A CHLORIDE IN THE PRESENCE OF AN ALKALI METAL SALT AND A SOLVENT | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0675130-A2 | Process for the preparation of phosphonium salts | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-10-04 | — | — | EP | disclosed |