Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.60 |
| ▸ | CA2 | P00918 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146937 | 0.88 | CYP3A4 (0.68) | ALDH1A1CYP3A4CA2TSHRTDP1 | |
| SCHEMBL14625765 | 0.88 | CYP3A4 (0.68) | ALDH1A1CYP3A4CA2TSHRTDP1 | |
| Ammonia Solution, Strong SCHEMBL1878882 | 0.87 | CYP3A4 (0.66) | ALDH1A1CYP3A4CA2TSHRTDP1 | |
| SCHEMBL10930013 | 0.87 | CYP3A4 (0.66) | ALDH1A1CYP3A4CA2TSHRTDP1 | |
| SCHEMBL28146062 | 0.87 | CYP3A4 (0.66) | ALDH1A1CYP3A4CA2TSHRTDP1 | |
| Acetic Acid SCHEMBL28184357 | 0.85 | CYP3A4 (0.64) | ALDH1A1CYP3A4CA2TSHRTDP1 | |
| SCHEMBL8679745 | 0.85 | ALDH1A1 (0.73) | ALDH1A1CYP3A4CA2TSHRTDP1 | |
| SCHEMBL28748130 | 0.83 | CYP3A4 (0.61) | ALDH1A1CYP3A4CA2TSHRTDP1 | |
| Acetophenone SCHEMBL23161891 | 0.82 | ALDH1A1 (0.62) | ALDH1A1CYP3A4CA2TSHRTDP1 | |
| Phosphoric Acid SCHEMBL28839428 | 0.82 | CYP3A4 (0.60) | ALDH1A1CYP3A4CA2TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856508-A | Fluorescent yellow 1,2,3,4-Tetrachloro-11H-Isoindolo- 2,1-A!-Benzimidazol-11-one pigments | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-01-05 | — | — | US | disclosed |
| EP-0456609-A1 | Fluorescent yellow 1,2,3,4-tetrachloro-11H-isoindolo-[2,1-a]-benzimidazol-11-one pigments | CIBA-GEIGY AG (CH) | 1991-11-13 | — | — | EP | disclosed |