Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.42 |
| ▸ | EGLN2 | Q96KS0 | 7/20 | 0.38 |
| ▸ | PDE4A | P27815 | 3/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8444288 | 0.74 | TRPV4 (0.45) | TRPV4EGLN2PDE4APDE4BPDE4C | |
| SCHEMBL7967445 | 0.73 | TRPV4 (0.37) | TRPV4EGLN2PDE4APDE4BPDE4C | |
| SCHEMBL8441483 | 0.73 | CYP11B1 (0.35) | TRPV4EGLN2PDE4APDE4BPDE4C | |
| SCHEMBL8436898 | 0.70 | EGLN2 (0.33) | TRPV4EGLN2PDE4APDE4BPDE4C | |
| SCHEMBL8604204 | 0.70 | EGLN2 (0.33) | TRPV4EGLN2PDE4APDE4BPDE4C | |
| SCHEMBL8444200 | 0.70 | TRPV4 (0.39) | TRPV4EGLN2PDE4APDE4BPDE4C | |
| SCHEMBL7162190 | 0.69 | EGLN2 (0.33) | TRPV4EGLN2 | |
| SCHEMBL7161842 | 0.69 | EGLN2 (0.32) | TRPV4EGLN2 | |
| SCHEMBL8441446 | 0.69 | EGLN2 (0.37) | TRPV4EGLN2PDE4APDE4BPDE4C | |
| SCHEMBL20444106 | 0.69 | TRPV4 (0.60) | TRPV4EGLN2PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906285-A1 | 3-CYANOARYL PYRAZOLES AND USE THEREOF AS HERBICIDES | BAYER AG (DE) | 1999-04-07 | — | — | EP | disclosed |
| WO-1997046535-A1 | 3-CYANOARYL PYRAZOLES AND USE THEREOF AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-11 | — | — | WO | disclosed |