Urea

Urea

SCHEMBL8440374

CCCCCCCCCCOCCCCCCCCCC.NC(N)=O

nearest known ligand 0.61

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Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.61
HTT P42858 2/20 0.60
MEN1 O00255 1/20 0.60
THRB P10828 1/20 0.60
KMT2A Q03164 1/20 0.60
MAPT P10636 1/20 0.60
NAAA Q02083 1/20 0.52
EPHX1 P07099 1/20 0.48
TSHR P16473 3/20 0.48
USP2 O75604 1/20 0.47
CA1 P00915 4/20 0.46
CA2 P00918 4/20 0.46
CA9 Q16790 4/20 0.46
LPAR1 Q92633 2/20 0.46
LPAR3 Q9UBY5 2/20 0.46
LPAR2 Q9HBW0 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL10987562 1.00 CES2 (0.61) CES2HTTMEN1THRBKMT2A
Urea SCHEMBL11670368 1.00 CES2 (0.61) CES2HTTMEN1THRBKMT2A
Urea SCHEMBL11670658 0.95 CES2 (0.57) CES2HTTMEN1THRBKMT2A
Urea SCHEMBL27771105 0.90 TSHR (0.59) CES2HTTMEN1THRBKMT2A
Urea SCHEMBL8373138 0.90 TSHR (0.59) CES2HTTMEN1THRBKMT2A
SCHEMBL28516282 0.89 MEN1 (0.59) CES2HTTMEN1THRBKMT2A
SCHEMBL25769633 0.89 CES2 (0.67) CES2HTTMEN1THRBKMT2A
SCHEMBL14389204 0.89 MEN1 (0.59) CES2HTTMEN1THRBKMT2A
SCHEMBL21341595 0.89 CES2 (0.67) CES2HTTMEN1THRBKMT2A
SCHEMBL27956888 0.89 MEN1 (0.59) CES2HTTMEN1THRBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0966194-A1 CONCENTRATED DISINFECTANT COMPOSITIONS Reckitt Benckiser Inc. (US) 1999-12-29 EP disclosed
WO-1998037760-A1 CONCENTRATED DISINFECTANT COMPOSITIONS RECKITT & COLMAN INC. (US) 1998-09-03 WO disclosed