Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KCNJ1 | P48048 | 4/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8439851 | 0.89 | KCNJ1 (0.61) | KDM4EALDH1A1TDP1MAPTKCNJ1 | |
| Hydrochloric Acid SCHEMBL8435792 | 0.88 | KCNJ1 (0.60) | KDM4EALDH1A1TDP1MAPTKCNJ1 | |
| Trifluoroacetic Acid SCHEMBL8435341 | 0.86 | KCNJ1 (0.48) | KDM4EALDH1A1TDP1MAPTKCNJ1 | |
| Trifluoroacetic Acid SCHEMBL8438033 | 0.81 | KCNJ1 (0.47) | KDM4EALDH1A1TDP1MAPTKCNJ1 | |
| SCHEMBL9124661 | 0.80 | KCNJ1 (0.53) | KDM4EALDH1A1TDP1MAPTKCNJ1 | |
| Trifluoroacetic Acid SCHEMBL6046649 | 0.77 | KCNJ1 (0.48) | KDM4EALDH1A1TDP1MAPTKCNJ1 | |
| SCHEMBL30435983 | 0.76 | KCNJ1 (0.55) | KDM4EALDH1A1TDP1MAPTKCNJ1 | |
| SCHEMBL14477660 | 0.76 | KCNJ1 (0.58) | KDM4EALDH1A1TDP1MAPTKCNJ1 | |
| SCHEMBL14312170 | 0.76 | KCNJ1 (0.58) | KDM4EALDH1A1TDP1MAPTKCNJ1 | |
| SCHEMBL9126753 | 0.75 | KCNJ1 (0.58) | KDM4EALDH1A1TDP1MAPTKCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0518558-B1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | SANKYO CO (JP) | 1998-09-02 | — | — | EP | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |
| US-5420119-A | Bactericides | SANKYO COMPANY, LIMITED (JP) | 1995-05-30 | — | — | US | disclosed |
| US-5310735-A | Carbapenem derivatives having antibiotic activity, their preparation and their use | SANKYO COMPANY, LIMITED (JP) | 1994-05-10 | — | — | US | disclosed |
| EP-0518558-A1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | Sankyo Company Limited (JP) | 1992-12-16 | — | — | EP | disclosed |
| EP-0443883-A1 | Carbapenem derivatives having antibiotic activity, their preparation and their use | Sankyo Company Limited (JP) | 1991-08-28 | — | — | EP | disclosed |