Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9124661 | 0.94 | KCNJ1 (0.53) | KCNJ1KCNH2ALDH1A1MAPTKDM4E | |
| SCHEMBL9126753 | 0.89 | KCNJ1 (0.58) | KCNJ1KCNH2ALDH1A1MAPTKDM4E | |
| Trifluoroacetic Acid SCHEMBL8440377 | 0.86 | KDM4E (0.53) | KCNJ1KCNH2ALDH1A1MAPTKDM4E | |
| SCHEMBL14312197 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4ETDP1LMNA | |
| SCHEMBL14477660 | 0.85 | KCNJ1 (0.58) | KCNJ1KCNH2ALDH1A1MAPTKDM4E | |
| SCHEMBL14312170 | 0.85 | KCNJ1 (0.58) | KCNJ1KCNH2ALDH1A1MAPTKDM4E | |
| Trifluoroacetic Acid SCHEMBL8438033 | 0.84 | KCNJ1 (0.47) | KCNJ1KCNH2ALDH1A1MAPTKDM4E | |
| SCHEMBL7169664 | 0.83 | LMNA (0.52) | KCNJ1KCNH2ALDH1A1MAPTLMNA | |
| SCHEMBL14477659 | 0.82 | KCNJ1 (0.54) | KCNJ1KCNH2ALDH1A1MAPTKDM4E | |
| Trifluoroacetic Acid SCHEMBL6046649 | 0.80 | KCNJ1 (0.48) | KCNJ1KCNH2ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0518558-B1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | SANKYO CO (JP) | 1998-09-02 | — | — | EP | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0518558-A1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | Sankyo Company Limited (JP) | 1992-12-16 | — | — | EP | disclosed |