SCHEMBL8440404

SCHEMBL8440404

O=P(O)(O)O[C@@H]1[C@@H](OP(=O)(O)O)[C@@H](OP(=O)(O)O)[C@@H](O)[C@H](O)[C@H]1OP(=O)(O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ITPR3 Q14573 8/20 1.00
ITPR2 Q14571 4/20 0.89
ITPR1 Q14643 4/20 0.89
INPP5A Q14642 2/20 0.84
INPPL1 O15357 1/20 0.84
AKT1 P31749 1/20 0.84
SMPD1 P17405 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12686382 1.00 ITPR3 (1.00) ITPR3ITPR2ITPR1INPP5AINPPL1
SCHEMBL1342025 1.00 ITPR3 (1.00) ITPR3ITPR2ITPR1INPP5AINPPL1
SCHEMBL513820 1.00 ITPR3 (1.00) ITPR3ITPR2ITPR1INPP5AINPPL1
SCHEMBL9439604 1.00 ITPR3 (1.00) ITPR3ITPR2ITPR1INPP5AINPPL1
SCHEMBL9439428 1.00 ITPR3 (1.00) ITPR3ITPR2ITPR1INPP5AINPPL1
SCHEMBL544343 1.00 ITPR3 (1.00) ITPR3ITPR2ITPR1INPP5AINPPL1
SCHEMBL356762 1.00 ITPR3 (1.00) ITPR3ITPR2ITPR1INPP5AINPPL1
Atrinositol SCHEMBL9022890 0.97 ITPR3 (1.00) ITPR3ITPR2ITPR1INPP5AINPPL1
Atrinositol SCHEMBL180074 0.97 ITPR3 (1.00) ITPR3ITPR2ITPR1INPP5AINPPL1
Atrinositol SCHEMBL888326 0.97 ITPR3 (1.00) ITPR3ITPR2ITPR1INPP5AINPPL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025132829-A1 BACTERIUM COMPRISING PHYTATE-DEGRADATION PATHWAY Stichting Amsterdam UMC (NL) 2025-06-26 WO disclosed
EP-0748210-B1 METHODS OF USING CYCLIC POLYANIONIC POLYOL DERIVATIVES FOR REGULATING SKIN WRINKLES PROCTER & GAMBLE (US) 1999-07-14 EP disclosed
US-5821237-A ACTIVE MATERIALS CONTAIN AT LEAST ONE CYCLIC POLYANIONIC POLYOL, AT LEAST ONE SULFYDRYL COMPOUND AND AT LEAST ONE ZWITTERIONIC SURFACTANT THE PROCTER & GAMBLE COMPANY (US) 1998-10-13 US disclosed
US-5434144-A Methods of using cyclic polyanionic polyol derivatives for regulating skin wrinkles THE PROCTER & GAMBLE COMPANY (US) 1995-07-18 US disclosed
US-5135923-A Inositol triphosphate PERSTORP AB (SE) 1992-08-04 US disclosed
US-5051411-A Administering inositol triphosphate for treatment of hypertension, immunodeficiency and dermatitis PERSTORP AB (SE) 1991-09-24 US disclosed
US-5023248-A Hydroglycemic agents, treatment of hyperketonemia and changes in lipid metabolism PERSTORP AB (SE) 1991-06-11 US disclosed
US-5019566-A Method of treating inflammation with inositol triphosphate PERSTORP AB (SE) 1991-05-28 US disclosed
US-4851560-A Inositol triphosphates PERSTORP AB (SE) 1989-07-25 US disclosed
US-4797390-A REDUCE NEGATIVE EFFECTS OF CADMIUM OR ALUMINUM PERSTORP AB (SE) 1989-01-10 US disclosed
US-4793945-A STABILIZING ORGANIC SUBSTRATE SUBJECT TO DEGRADATION BY OXIDATION AND-OR FREE RADICAL REACTION PERSTORP AB (SE) 1988-12-27 US disclosed
US-4794014-A COUNTERACTING DELITERIOUS EFFECTS OF HEAVY METALS, RADIATION AND SMOKING PERSTORP AB (SE) 1988-12-27 US disclosed
US-4735902-A ORGANIC SUBSTRATES SUBJECT TO DEGRADATION BY OXIDATION OR FREE RADICALS PERSTORP AB (SE) 1988-04-05 US disclosed
US-4735936-A FREE RADICAL INHIBITION IN THE BODY PERSTORP AB (SE) 1988-04-05 US disclosed
EP-0179441-A2 A method of making a food composition containing inositoltriphosphate and the composition Sirén, Matti (CH) 1986-04-30 EP disclosed
EP-0179442-A2 Stabilized composition containing inositoltriphosphate and method for stabilizing the composition PERSTORP AB (SE) 1986-04-30 EP disclosed
EP-0179439-A1 A pharmaceutical composition and a method for preparing same Sirén, Matti (CH) 1986-04-30 EP disclosed