Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.30 |
| ▸ | WDR5 | P61964 | 1/20 | 0.30 |
| ▸ | CD38 | P28907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3488529 | 1.00 | KDM2B (0.39) | KDM2BCYP19A1HTR2AHTR2CHTR2B | |
| SCHEMBL14254669 | 1.00 | KDM2B (0.39) | KDM2BCYP19A1HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL30232427 | 1.00 | KDM2B (0.39) | KDM2BCYP19A1HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL1994942 | 1.00 | KDM2B (0.39) | KDM2BCYP19A1HTR2AHTR2CHTR2B | |
| SCHEMBL2675534 | 0.89 | HTR6 (0.35) | KDM2BCYP19A1HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL3862147 | 0.88 | MEN1 (0.38) | CYP19A1MEN1ALDH1A1MAPTPKM | |
| SCHEMBL1993621 | 0.88 | MEN1 (0.38) | CYP19A1MEN1ALDH1A1MAPTPKM | |
| Hydrochloric Acid SCHEMBL7401834 | 0.84 | CYP19A1 (0.37) | CYP19A1CYP2B6 | |
| SCHEMBL1650652 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL8439976 | 0.84 | CYP19A1 (0.37) | CYP19A1CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7342016-B2 | Farnesyl protein transferase inhibitors as antitumor agents | SCHERING CORPORATION (US) | 2008-03-11 | — | — | US | disclosed |
| US-7342016-B2 | Farnesyl protein transferase inhibitors as antitumor agents | SCHERING CORPORATION (US) | 2008-03-11 | — | — | US | disclosed |
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |
| CN-1030767-C | 1-methylcarbapenem derivatives, their preparation and their use as antibiotics | SANKYO CO (JP) | 1996-01-24 | — | — | CN | disclosed |