⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21782896 | 0.80 | — | — | |
| SCHEMBL20663394 | 0.78 | — | — | |
| SCHEMBL13309812 | 0.78 | — | — | |
| SCHEMBL30605494 | 0.78 | — | — | |
| SCHEMBL13282614 | 0.78 | — | — | |
| SCHEMBL22221861 | 0.77 | — | — | |
| SCHEMBL20663160 | 0.73 | — | — | |
| SCHEMBL21650444 | 0.71 | NOS1 (0.33) | — | |
| SCHEMBL22561643 | 0.71 | — | — | |
| SCHEMBL17414787 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023072966-A1 | IMIDAZOLONE DERIVATIVES AS INHIBITORS OF PROTEIN KINASES IN PARTICULAR DYRK1A, CLK1 AND/OR CLK4 | PERHA PHARMACEUTICALS (FR) | 2023-05-04 | — | — | WO | disclosed |
| EP-3930043-A1 | NONAQUEOUS ELECTROLYTE, NONAQUEOUS SECONDARY BATTERY, CELL PACK, AND HYBRID SYSTEM | Asahi Kasei Kabushiki Kaisha (JP) | 2021-12-29 | — | — | EP | disclosed |
| WO-2011154586-A2 | IMPROVED METHODS FOR THE PREPARATION OF QUINOXALINE DERIVATIVES | MEDICHEM, S. A. (ES) | 2011-12-15 | — | — | WO | disclosed |
| WO-2011099832-A2 | NOVEL BENZIMIDAZOLE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CRYSTALGENOMICS, INC. (KR) | 2011-08-18 | — | — | WO | disclosed |
| EP-2152674-B1 | BENZIMIDAZOLONE CHYMASE INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010123139-A1 | ARYLCARBOXAMIDE DERIVATIVE HAVING SULFAMOYL GROUP | 持田製薬株式会社 (JP) | 2010-10-28 | — | — | WO | disclosed |
| EP-2236503-A1 | Cinamic compounds and derivatives therefrom for the inhibition of histone deacetylase | NatureWise Biotech & Medicals Corporation (TW) | 2010-10-06 | — | — | EP | disclosed |