Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 11/20 | 0.41 |
| ▸ | GRM6 | O15303 | 6/20 | 0.41 |
| ▸ | GRM3 | Q14832 | 6/20 | 0.41 |
| ▸ | GRM8 | O00222 | 2/20 | 0.41 |
| ▸ | ARG1 | P05089 | 4/20 | 0.41 |
| ▸ | ARG2 | P78540 | 2/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 5/20 | 0.40 |
| ▸ | GRM5 | P41594 | 6/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441724 | 1.00 | GRM2 (0.41) | GRM2GRM6GRM3GRM8ARG1 | |
| SCHEMBL8443338 | 1.00 | GRM2 (0.41) | GRM2GRM6GRM3GRM8ARG1 | |
| SCHEMBL22415975 | 1.00 | GRM2 (0.41) | GRM2GRM6GRM3GRM8ARG1 | |
| SCHEMBL8438917 | 1.00 | GRM2 (0.41) | GRM2GRM6GRM3GRM8ARG1 | |
| SCHEMBL8442848 | 0.98 | GRM2 (0.40) | GRM2GRM6GRM3GRM8ARG1 | |
| SCHEMBL8441716 | 0.98 | GRM2 (0.40) | GRM2GRM6GRM3GRM8ARG1 | |
| SCHEMBL8438555 | 0.98 | GRM2 (0.40) | GRM2GRM6GRM3GRM8ARG1 | |
| SCHEMBL8442846 | 0.98 | GRM2 (0.40) | GRM2GRM6GRM3GRM8ARG1 | |
| SCHEMBL6294440 | 0.93 | ARG1 (0.46) | GRM2GRM6GRM3GRM8ARG1 | |
| SCHEMBL6300310 | 0.93 | ARG1 (0.46) | GRM2GRM6GRM3GRM8ARG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5959141-A | 1-amino-2-hydroxycycloalkanecarboxylic acid derivatives | SUNTORY LIMITED (JP) | 1999-09-28 | — | — | US | disclosed |