Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.63 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.63 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 10/20 | 0.51 |
| ▸ | MEN1 | O00255 | 10/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.51 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 8/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 6/20 | 0.46 |
| ▸ | GFER | P55789 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441229 | 1.00 | ALDH1A1 (0.63) | ALDH1A1ALDH3A1ALDH1A3GAAKDM4E | |
| SCHEMBL19287553 | 0.81 | ALDH1A1 (0.61) | ALDH1A1ALDH3A1ALDH1A3GAAKDM4E | |
| SCHEMBL8437202 | 0.79 | HDAC3 (0.60) | ALDH1A1GAATSHRMAPTMEN1 | |
| SCHEMBL8437200 | 0.79 | HDAC3 (0.60) | ALDH1A1GAATSHRMAPTMEN1 | |
| SCHEMBL15145056 | 0.79 | ALDH1A1 (0.59) | ALDH1A1ALDH3A1ALDH1A3GAAKDM4E | |
| SCHEMBL10981269 | 0.79 | ALDH1A1 (0.58) | ALDH1A1ALDH3A1ALDH1A3GAAKDM4E | |
| SCHEMBL10981268 | 0.79 | ALDH1A1 (0.58) | ALDH1A1ALDH3A1ALDH1A3GAAKDM4E | |
| SCHEMBL195135 | 0.78 | ALDH1A1 (1.00) | ALDH1A1ALDH3A1ALDH1A3GAAKDM4E | |
| SCHEMBL5733313 | 0.78 | ALDH1A1 (1.00) | ALDH1A1ALDH3A1ALDH1A3GAAKDM4E | |
| SCHEMBL19141845 | 0.78 | ALDH1A1 (0.58) | ALDH1A1ALDH3A1ALDH1A3GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419095-B1 | Radiation sensitive compositions | AGFA GEVAERT NV (BE) | 1999-12-29 | — | — | EP | disclosed |
| US-5264329-A | Radiation sensitive compositions | DUPONT (U.K.) LIMITED (GB) | 1993-11-23 | — | — | US | disclosed |
| US-5130228-A | Photosensitive material, a dye which will change color on radiation, a multilayer device | DUPONT-HOWSON LIMITED (GB) | 1992-07-14 | — | — | US | disclosed |
| EP-0419095-A2 | Radiation sensitive compositions | Du Pont (UK) Limited (GB) | 1991-03-27 | — | — | EP | disclosed |