Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGAM1 | P18669 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10024271 | 0.81 | PGAM1 (0.48) | PGAM1 | |
| SCHEMBL12758262 | 0.76 | KDM4E (0.56) | — | |
| SCHEMBL10024295 | 0.76 | — | — | |
| SCHEMBL10024277 | 0.75 | — | — | |
| SCHEMBL14557527 | 0.75 | MEN1 (0.49) | — | |
| SCHEMBL10024272 | 0.74 | — | — | |
| SCHEMBL11442426 | 0.74 | PGAM1 (0.52) | PGAM1 | |
| SCHEMBL10024321 | 0.73 | — | — | |
| SCHEMBL10886862 | 0.73 | PGAM1 (0.51) | PGAM1 | |
| SCHEMBL14557528 | 0.72 | KDM4E (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0966436-A1 | ARYL SULFONAMIDES AND ANALOGUES THEREOF AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | Bayer Aktiengesellschaft (DE) | 1999-12-29 | — | — | EP | disclosed |
| WO-1998037061-A1 | ARYL SULFONAMIDES AND ANALOGUES THEREOF AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-08-27 | — | — | WO | disclosed |