Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 2/20 | 0.35 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.33 |
| ▸ | GRB2 | P62993 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | GRM8 | O00222 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GSR | P00390 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8722447 | 1.00 | CA2 (0.37) | CA2CA1PMP22PTGS1SLC7A11 | |
| SCHEMBL1769061 | 0.81 | PMP22 (0.40) | PMP22PTGS1SLC7A11CASRGFPT1 | |
| SCHEMBL28095363 | 0.81 | PMP22 (0.40) | PMP22PTGS1SLC7A11CASRGFPT1 | |
| SCHEMBL1768824 | 0.78 | SLC7A5 (0.35) | PMP22PTGS1SLC7A11CASRGFPT1 | |
| SCHEMBL27888832 | 0.78 | SLC7A5 (0.35) | PMP22PTGS1SLC7A11CASRGFPT1 | |
| SCHEMBL1769806 | 0.77 | PMP22 (0.33) | PMP22PTGS1SLC7A11CASRGFPT1 | |
| SCHEMBL1769809 | 0.77 | PMP22 (0.33) | PMP22PTGS1SLC7A11CASRGFPT1 | |
| SCHEMBL1768840 | 0.75 | PTGS1 (0.41) | PMP22PTGS1SLC7A11CASRGFPT1 | |
| SCHEMBL1768843 | 0.75 | PTGS1 (0.41) | PMP22PTGS1SLC7A11CASRGFPT1 | |
| SCHEMBL1823399 | 0.75 | PTGS1 (0.41) | PMP22PTGS1SLC7A11CASRGFPT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0896003-A1 | Peptides for reducing or inhibiting bone resorption, angiogenesis and restenosis | LA JOLLA CANCER RESEARCH FOUNDATION (US) | 1999-02-10 | — | — | EP | disclosed |
| WO-1998016256-A1 | MAGNETIC RESONANCE IMAGING OF THROMBI | THE BURNHAM INSTITUTE (US) | 1998-04-23 | — | — | WO | disclosed |
| EP-0755408-A1 | PEPTIDES FOR REDUCING OR INHIBITING BONE RESORPTION, ANGIOGENESIS AND RESTENOSIS | LA JOLLA CANCER RESEARCH FOUNDATION (US) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995028426-A2 | PEPTIDES FOR REDUCING OR INHIBITING BONE RESORPTION, ANGIOGENESIS AND RESTENOSIS | LA JOLLA CANCER RESEARCH FOUNDATION (US) | 1995-10-26 | — | — | WO | disclosed |