Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2110048 | 1.00 | LMNA (0.39) | LMNARARBALDH1A1KDM4CKDM4A | |
| SCHEMBL8811504 | 1.00 | LMNA (0.39) | LMNARARBALDH1A1KDM4CKDM4A | |
| SCHEMBL93134 | 1.00 | LMNA (0.39) | LMNARARBALDH1A1KDM4CKDM4A | |
| SCHEMBL93187 | 1.00 | LMNA (0.39) | LMNARARBALDH1A1KDM4CKDM4A | |
| SCHEMBL2110029 | 1.00 | LMNA (0.39) | LMNARARBALDH1A1KDM4CKDM4A | |
| SCHEMBL93166 | 1.00 | LMNA (0.39) | LMNARARBALDH1A1KDM4CKDM4A | |
| SCHEMBL2109724 | 1.00 | LMNA (0.39) | LMNARARBALDH1A1KDM4CKDM4A | |
| SCHEMBL2109678 | 1.00 | LMNA (0.39) | LMNARARBALDH1A1KDM4CKDM4A | |
| SCHEMBL5145733 | 1.00 | LMNA (0.39) | LMNARARBALDH1A1KDM4CKDM4A | |
| SCHEMBL2109218 | 1.00 | LMNA (0.39) | LMNARARBALDH1A1KDM4CKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5871895-A | 1H-PYRROLO(1,2-C)(1,2,3-)TRIAZOLE BASED DYE-FORMING COUPLER; LIGHTFASTNESS, COLOR REPRODUCIBILITY, DISCOLORATION INHIBITION | FUJI PHOTO FILM CO., LTD. (JP) | 1999-02-16 | — | — | US | disclosed |
| US-5691319-A | ANTICARCINOGENIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0536936-B1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | SANKYO CO (JP) | 1996-08-14 | — | — | EP | disclosed |
| US-5500334-A | Silver halide color photographic material containing pyrazole-substituted couplers | FUJI PHOTO FILM CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| EP-0536936-A1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | Sankyo Company Limited (JP) | 1993-04-14 | — | — | EP | disclosed |
| US-4859759-A | Siloxane containing benzotriazolyl/tetraalkylpiperidyl substituent | KIMBERLY-CLARK CORPORATION (US) | 1989-08-22 | — | — | US | disclosed |