Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | IL2 | P60568 | 1/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CDK8 | P49336 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 2/20 | 0.48 |
| ▸ | SDHB | P21912 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27108460 | 0.84 | ALDH1A1 (0.55) | TP53SMN1; SMN2CA12CA1CA2 | |
| SCHEMBL28716472 | 0.84 | CNR1 (0.55) | CNR1TP53SMN1; SMN2IL2GABRG2 | |
| SCHEMBL8443409 | 0.84 | CNR1 (0.61) | CNR1TP53SMN1; SMN2IL2GABRG2 | |
| SCHEMBL10154904 | 0.83 | CNR1 (0.53) | CNR1CDK8 | |
| SCHEMBL6253921 | 0.83 | HDAC1 (0.60) | CNR1SMN1; SMN2NPC1GAA | |
| SCHEMBL67941 | 0.80 | CA12 (0.68) | GABRG2GABRB3GABRA5GABRA3CA12 | |
| SCHEMBL22834236 | 0.79 | CNR1 (0.51) | CNR1TP53SMN1; SMN2IL2GABRG2 | |
| SCHEMBL13571522 | 0.79 | CA1 (0.60) | CNR1TP53SMN1; SMN2CA12CA1 | |
| SCHEMBL10150917 | 0.79 | CNR1 (0.47) | CNR1NPC1GAAMAPT | |
| SCHEMBL16086265 | 0.78 | CSNK2A1 (0.55) | CNR1SMN1; SMN2GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968985-A | INHIBITORS OF SODIUM ION/HYDROGEN ION EXCHANGE IN CELLS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| EP-0773927-A2 | BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996004241-A2 | BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-15 | — | — | WO | disclosed |