SCHEMBL8444017

SCHEMBL8444017

CC(C)(c1ccccc1)c1ccc(OP(Cl)Cl)c(C(C)(C)c2ccccc2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.44
ESR2 Q92731 5/20 0.44
CYP3A4 P08684 2/20 0.44
ALDH1A1 P00352 1/20 0.44
CNR1 P21554 4/20 0.42
CNR2 P34972 4/20 0.42
SMN1; SMN2 Q16637 1/20 0.36
NR3C2 P08235 3/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
AR P10275 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
HTR6 P50406 1/20 0.33
ESRRG P62508 1/20 0.33
SLC6A3 Q01959 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2242839 0.87 ALDH1A1 (0.43) ESR1ESR2CYP3A4ALDH1A1CNR1
SCHEMBL12151600 0.84 ALDH1A1 (0.41) ESR1ESR2CYP3A4ALDH1A1CNR1
SCHEMBL29389008 0.84 ALDH1A1 (0.44) ESR1ESR2CYP3A4ALDH1A1CNR1
SCHEMBL2242844 0.84 ALDH1A1 (0.44) ESR1ESR2CYP3A4ALDH1A1CNR1
SCHEMBL29286983 0.84 ALDH1A1 (0.44) ESR1ESR2CYP3A4ALDH1A1CNR1
SCHEMBL31442122 0.84 ALDH1A1 (0.44) ESR1ESR2CYP3A4ALDH1A1CNR1
SCHEMBL15423891 0.83 ALDH1A1 (0.46) ESR1ESR2CYP3A4ALDH1A1CNR1
Hydrochloric Acid SCHEMBL28561683 0.83 ALDH1A1 (0.43) ESR1ESR2CYP3A4ALDH1A1CNR1
SCHEMBL24633257 0.82 ALDH1A1 (0.39) ESR1ESR2CYP3A4ALDH1A1CNR1
SCHEMBL28611764 0.82 ALDH1A1 (0.47) ESR1ESR2CYP3A4ALDH1A1CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0680486-B1 HYDROLYTICALLY STABLE PENTAERYTHRITOL DIPHOSPHITES DOVER CHEMICAL CORP (US) 1999-03-24 EP claimed
EP-0680486-B1 HYDROLYTICALLY STABLE PENTAERYTHRITOL DIPHOSPHITES DOVER CHEMICAL CORP (US) 1999-03-24 EP disclosed