Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7775479 | 0.93 | HDAC8 (0.52) | HDAC8PTPN1MAPTMEN1LMNA | |
| SCHEMBL7776748 | 0.93 | HDAC8 (0.62) | HDAC8PTPN1MAPTMEN1LMNA | |
| SCHEMBL7775563 | 0.93 | HDAC8 (0.52) | HDAC8PTPN1MAPTMEN1LMNA | |
| SCHEMBL7775518 | 0.93 | HDAC8 (0.62) | HDAC8PTPN1MAPTMEN1LMNA | |
| SCHEMBL30039059 | 0.93 | HDAC8 (0.62) | HDAC8PTPN1MAPTMEN1LMNA | |
| SCHEMBL7775463 | 0.92 | HDAC8 (0.51) | HDAC8PTPN1MAPTMEN1LMNA | |
| SCHEMBL7780908 | 0.92 | HDAC8 (0.51) | HDAC8PTPN1MAPTMEN1LMNA | |
| SCHEMBL7776299 | 0.92 | HDAC8 (0.51) | HDAC8PTPN1MAPTMEN1LMNA | |
| SCHEMBL7775559 | 0.92 | HDAC8 (0.51) | HDAC8PTPN1MAPTMEN1LMNA | |
| SCHEMBL7776750 | 0.92 | HDAC8 (0.50) | HDAC8PTPN1MAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2236503-A1 | Cinamic compounds and derivatives therefrom for the inhibition of histone deacetylase | NatureWise Biotech & Medicals Corporation (TW) | 2010-10-06 | — | — | EP | disclosed |