Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7455301 | 1.00 | DPP8 (0.40) | DPP8DPP9ALDH1A1GAAHTR2A | |
| SCHEMBL8448876 | 0.83 | GAA (0.39) | DPP8DPP9ALDH1A1GAAHTR2A | |
| SCHEMBL7453980 | 0.83 | GAA (0.39) | DPP8DPP9ALDH1A1GAAHTR2A | |
| SCHEMBL8449102 | 0.82 | DPP8 (0.35) | DPP8DPP9ALDH1A1GAAHTR2A | |
| SCHEMBL8444873 | 0.82 | DPP8 (0.35) | DPP8DPP9ALDH1A1GAAHTR2A | |
| SCHEMBL8444875 | 0.81 | DPP8 (0.34) | DPP8DPP9ALDH1A1GAAHTR2A | |
| SCHEMBL8435987 | 0.81 | HSD11B1 (0.44) | DPP8DPP9ALDH1A1KMT2AATM | |
| SCHEMBL8435984 | 0.81 | HSD11B1 (0.44) | DPP8DPP9ALDH1A1KMT2AATM | |
| SCHEMBL7455314 | 0.80 | DPP8 (0.43) | DPP8DPP9ALDH1A1GAAHTR2A | |
| SCHEMBL7455307 | 0.80 | DPP8 (0.43) | DPP8DPP9ALDH1A1GAAHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977097-A | 1-methylcarbapenem derivatives | SANKYO COMPANY LIMITED (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0900797-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1999-03-10 | — | — | EP | disclosed |