SCHEMBL8444906

SCHEMBL8444906

C=CC=CC(=O)CCCC

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.59
KDM4E B2RXH2 1/20 0.46
POLB P06746 1/20 0.43
POLA1 P09884 1/20 0.43
OXER1 Q8TDS5 5/20 0.42
ALOX12 P18054 2/20 0.42
CES1 P23141 2/20 0.42
CES2 O00748 1/20 0.42
IAPP P10997 2/20 0.42
PPARG P37231 2/20 0.42
PPARA Q07869 2/20 0.42
FAAH O00519 1/20 0.40
ALOX5 P09917 1/20 0.40
ALDH1A1 P00352 1/20 0.39
TP53 P04637 1/20 0.39
CA1 P00915 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8444903 1.00 TRPA1 (0.59) TRPA1KDM4EPOLBPOLA1OXER1
SCHEMBL11526132 0.94 TRPA1 (0.68) TRPA1KDM4EPOLBPOLA1OXER1
SCHEMBL11526130 0.94 TRPA1 (0.68) TRPA1KDM4EPOLBPOLA1OXER1
SCHEMBL2998071 0.92 TRPA1 (0.55) TRPA1KDM4EPOLBPOLA1OXER1
SCHEMBL3004067 0.92 TRPA1 (0.55) TRPA1KDM4EPOLBPOLA1OXER1
SCHEMBL11530479 0.92 TRPA1 (0.66) TRPA1KDM4EPOLBPOLA1ALOX12
SCHEMBL2998074 0.92 TRPA1 (0.55) TRPA1KDM4EPOLBPOLA1OXER1
SCHEMBL5912083 0.92 TRPA1 (0.66) TRPA1KDM4EPOLBPOLA1ALOX12
SCHEMBL11530476 0.92 TRPA1 (0.66) TRPA1KDM4EPOLBPOLA1ALOX12
SCHEMBL11524030 0.92 TRPA1 (0.66) TRPA1KDM4EPOLBPOLA1ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119453193-A Composition for removing natural enemy ants of termites, application of composition, device and slow-release product for attracting termites 浙江瀚达环境科技有限公司 2025-02-18 CN claimed
CN-119453193-A Composition for removing natural enemy ants of termites, application of composition, device and slow-release product for attracting termites 浙江瀚达环境科技有限公司 2025-02-18 CN disclosed
US-5929247-A METHODS OF SYNTHESIZING 1,2,5-THIADIAZOLE COMPOUNDS SUCH AS 3-PROPYLTHIO-4-HYDROXY-1,2,5-THIADIAZOLE, USEFUL IN TREATING DISEASES IN THE CENTRAL NERVOUS SYSTEM CAUSED BY MUSCARINIC CHOLINERGIC SYSTEM MALFUNCTIONING ELI LILLY AND COMPANY (US) 1999-07-27 US disclosed
US-5852037-A Method for treating anxiety ELI LILLY AND COMPANY (US) 1998-12-22 US disclosed
US-5821370-A MUSCARINIC CHOLINERGIC DRUGS ELI LILLY AND COMPANY (US) 1998-10-13 US disclosed
US-5821371-A 1,2,5-THIADIAZOLE COMPOUNDS USEFUL IN THE TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM CAUSED BY MALFUNCTIONING OF THE MUSCARINIC CHOLINERGIC SYSTEM; COGNITION ACTIVATORS; ALZHEIMER'S DISEASE ELI LILLY AND COMANY (US) 1998-10-13 US disclosed
US-5672709-A INTERMEDIATES FOR DRUGS USEFUL IN TREATING CENTRAL NERVOUS SYSTEM DISORDERS ELI LILLY AND COMPANY (US) 1997-09-30 US disclosed
US-4161608-A 11 Hydroxy methyl 11-deoxyprostaglandin E1 AYERST, MCKENNA AND HARRISON LIMITED (CA) 1979-07-17 US disclosed
US-4100343-A 11-Deoxyprostaglandin derivatives AYERST, MCKENNA & HARRISON LIMITED (CA) 1978-07-11 US disclosed
US-4089898-A 11-Deoxyprostaglandin derivatives AYERST, MCKENNA & HARRISON LTD. (CA) 1978-05-16 US disclosed
US-4036856-A PROSTAGLANDINS AYERST MCKENNA AND HARRISON LTD. (CA) 1977-07-19 US disclosed
US-4006136-A Prostaglandin intermediates AYERST MCKENNA AND HARRISON LTD. (CA) 1977-02-01 US disclosed